ABSTRACT
The central nervous system ( CNS) complications and peripheral nervous system ( PNS) complications are common complications of sepsis. CNS complications include sepsis associated encephalopathy (SAE),septic-metastatic encephalitis (SME),and septic-embolic encephalitis (SEE). Of them,the SAE is the most common complication of CNS complications. PNS complications include critical illness polyneuropathy (CIP) and critical illness myopathy (CIM). CIP and CIM could lead to muscle weakness and dependence on mechanical ventilation of patients with sepsis. Sepsis related neurological complications are closely related to the mortality and prognosis of patients,so early recognition and timely intervention are important.
ABSTRACT
Septic encephalopathy( SE) is defined as diffuse brain dysfunction that related to systemic inflammatory response and without clinical or laboratory evidence of central nervous system infection.SE is one of the most common complications of patients with severe sepsis.Its pathogenesis is very complex and is not yet clear.The clinical manifestations of SE varied and have no specificity, mainly for changes of con-sciousness and mental status.The performance of electroencephalography is more sensitive,and is associated with prognosis.Somatosensory evoked potentials could display the damage of cortical or subcortical path-ways.Brain MRI has a more accurate assessment of the nature and the extent of brain damage.SE is a diag-nosis of exclusion.Before the diagnosis of SE,we need to exclude other encephalitis and encephalopathy.The morbidity and mortality of SE are high.It requires close attention,early detection and timely treatment.